ONLINE Live Six Week Training: Essential Oils for Healing Persistent Lyme Symptoms for Medical Providers

Learn to Reduce Persistent Symptoms Faster in Your Lyme Disease Patients Through Essential Oils

– Do you have Lyme patients that continue to report recurring pain, fatigue and mental fog?

– Are you frustrated by the lack of patient improvement with
Lyme protocols?

– Learn about safe amounts of essential oils for internal use
to treat stubborn Lyme symptoms.

Sign up by April 28th and receive a BONUS cold laser and an essential oil remedy laser kit for Lyme and other infection symptoms worth $100.

Participants will get six one-hour live training sessions every Friday 3pm – 4pm EST from April 29th – June 3rd. All sessions are recorded and available for replay 24/7. Participants will also get bonus videos on using cold laser essential oils and making liposomal essential oil remedies for resolving persistent Lyme symptoms.

You can see two videos, one on specific essential oils for Lyme and co-infections and a second of an indepth case study on how oils helped heal neurological Lyme disease and co-infections here:
https://goodbyelyme.com/training

Registration closes Thursday April 28th. Space is limited…
This training costs $900, which is 25% off the cost of the live event.

Questions about the training?
Please email me at TwoFrogsHealingCenter at gmail.com

– Greg

– Greg

>> Next step: Click here to take our What Lyme Brain Type are You? Quiz to help identify underlying causes of neurological Lyme.


P.S. Do you have experiences where sweeteners helped you to fight and heal Lyme disease and co-infections? Tell us about it.

DISCLAIMER:-

The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information is not intended to be patient education, does not create any patient-practitioner relationship, and should not be used as a substitute for professional diagnosis and treatment.

Please consult your health care provider, or contact the Two Frogs Healing Center for an appointment, before making any healthcare decisions or for guidance about a specific medical condition. The Two Frogs Healing Center expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. The Two Frogs Healing Center does not endorse specifically any test, treatment, or procedure mentioned on the site.

By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by the Two Frogs Healing Center. If you do not agree to the foregoing terms and conditions, you should not enter this site.

For people with Lyme disease and co-infections who feel toxic and have abnormal liver function tests
by Greg Lee

One of my mom’s coworkers loved to bake. Our family always looked forward to going over to her house especially for dinner. Coming in the front door, I’d always smell the aroma of fresh baked dessert. In the kitchen, we’d sometimes see my mom’s friend in her apron and oven mitts pulling her baked goods out of the oven.

How is a hot pie similar to Lyme disease toxins that can disrupt the liver?

Just like a hot pie that could burn you if you touched it, Lyme disease toxins can harm the healthy functioning of the liver
In multiple studies, people infected with Lyme disease have been diagnosed with liver problems including hepatitis,^[1] liver enlargement^[2], febrile jaundice, liver cytolytic and cholestatic abnormalities^[3], [4], abnormal liver function assays^[5], and elevated liver enzymes^[6]. Since a primary role of the liver is detoxification, how well it can detoxify has a direct impact on how sick or well a person feels from the toxins produced by Lyme disease. In alcoholic patients that have similar toxic liver issues, elevated levels of endotoxins and inflammatory compounds are common. These toxins can increase liver inflammation, fatty liver, scarring, and organ damage^[7]. Not only toxins from Lyme, but also genetics can have a dramatic impact on liver detoxification.

Genetics as well as Lyme can influence how well the liver can deal with toxins and medications
In one study, people with non-viral liver inflammation and chronic liver failure were more likely to have genetic mutations called MTHFR C677T, and PAI-1 4G-4G^[8]. In another study, people with non-alcoholic fatty liver disease had greater numbers of MTHFR C677T and MTHFR 1298A/C mutations^[9]. In a third study, people with the MTHFR C677T and A1298C were at higher risk of developing liver carcinoma in a study in China^[10]. Tuberculosis patients with genetic mutations NAT2, GST and CYP2E1 have greater incidence of antibiotic induced liver toxicity in one study^[11]. GST influences the production of glutathione which is an important detoxification compound in the liver and the whole body. A significant number of Lyme patients have genetic mutations which interfere with how well they detoxify and protect their liver. Liver function can also be influenced by antibiotic treatment for Lyme.

Antibiotic treatment for Lyme disease can have positive or negative effect on the liver
In one study, most patients with early Lyme disease that received antibiotics had liver function tests return to normal after three weeks of treatment^[12]. In other studies, patients undergoing antibiotic therapy for Lyme disease experienced negative side effects ranging from: mild liver function derangement^[13] and hepatitis and elevated liver enzymes^[14]. Lyme patients that are taking antibiotics that also test positive for abnormal liver function can be taken off their medications to protect their liver. Lyme disease stimulates the production of inflammatory compounds which can affect liver functioning.

Lyme disease can elevate inflammatory compounds that can impact the liver and other organs
Patients with Lyme disease have been found to have many elevated pro-inflammatory compounds including: Interleukin-6 (IL-6), IL-8, Tumor Necrosis Factor – alpha  (TNF-α)^[15], and C-Reactive Protein^[16]. IL-6 is actually elevated in liver regeneration^[17]. However, IL-6 is also a pathogenic factor in various autoimmune and chronic inflammatory diseases^[18]. Elevated levels of Il-8 have been found in patients with neurologic Lyme disease. Elevated C-reactive protein have been associated with a decline in mental function and frontal lobe damage^[19]. These inflammatory compounds can also dramatically affect the emotions of people with Lyme.

Liver dysfunction can also affect painful emotions
Painful emotions are directly attributed to dysfunction in the liver in Chinese medicine^[20]. There is a strong correlation between elevated liver enzymes and higher levels of C-Reactive Protein^[21]. In one study, depressed men had higher levels of inflammatory compounds IL-6 and C-Reactive Protein ^[22]. Another animal study correlates psycho-social stress with the production of inflammatory compounds Tumor Necrosis Factor – alpha (TNF-α) and IL-6 and increased liver inflammation^[23]. Depression and anxiety were the two most common emotions in a study on alcoholic patients with liver scarring^[24].

What else can help patients with Lyme or co-infection toxins that feel toxic and have abnormal liver function tests?

Here are four essential oils that are effective at protecting the liver and reducing inflammation
Fortunately, there are essential oils that protect the liver and reduce toxicity and inflammation in animal studies. Preparing the oils in a micronized form called a liposome, which are microscopic particles of medicinal oils that are wrapped in a sunflower lecithin compound called phosphatidylcholine may increase their effectiveness at protecting the liver when combined with a compound found in licorice^[25]. A liposomal herbal extract was more effective at delivering medicine into the liver compared to its non-liposomal equivalent^[26]. Which is why liposomal essential oils maybe more effective at helping patients with protecting the liver and detoxification.

Liver Protection Essential Oil #1: Black Cumin Seed Essential Oil
Black cumin seed essential oil demonstrated antioxidant properties which had a beneficial effect on liver enzymes in a rat study^[27]. In another study, this oil reduced TNF-α induced arthritis in another rat study^[28]. Black cumin seed oil also has demonstrated anti-inflammatory, analgesic, fever reducing, antimicrobial and anti-tumor activity. It also decreases blood pressure and increases respiration. This oil has been shown not to induce significant adverse effects on liver or kidney functions^[29]. Thymoquinone (TQ), a major active compound in black cumin seed oil, lowered inflammatory compounds IL-1β, IL-6, TNF-α, interferon-gamma (IFN-γ) and prostaglandin E2 (PGE2) and increased glutathione (GSH) in multiple rat studies^[30]. In another rat study, this oil increased tryptophan levels in the brain and decreased anxiety^[31] and depression^[32].  In addition to black cumin seed oil, ginger oil also protects the liver.

Liver Protection Essential Oil #2: Ginger Essential Oil
Ginger essential oil demonstrated liver protective properties in a mouse study.^[33] In another mouse study, this oil significantly increased glutathione and glutathione reductase enzymes in blood and glutathione-S-transferase, glutathione peroxidase and antioxidant enzymes in the liver. Ginger oil also significantly reduced acute inflammation^[34]. Ginger oil combined with magnolia extracts has an antidepressant effect in a rat study^[35]. This oil has been classified as generally recognized as safe (GRAS) by the US Food and Drug Administration (FDA)^[36]. Besides ginger, turmeric oil can help reduce inflammation from Lyme disease and co-infections.

Liver Protection Essential Oil #3: Turmeric Essential Oil
Turmeric essential oil reduced hepatic cholesterol and oxidative stress, and improved liver function in one hamster study^[37]. In another rat study, turmeric oil reduced endothelial cell induced inflammation^[38]. Endothelial cell inflammation is a recurring problem in patients with Babesia^[39], Bartonella, Ehrlichia, Anaplasmosis^[40], and Lyme arthritis that does not improve with antibiotic treatment^[41]. In a mouse study, turmeric oil increased superoxide dismutase, glutathione, and glutathione reductase enzyme levels in blood and glutathione-S-transferase and superoxide dismutase enzymes in the liver. This oil also demonstrated significant antioxidant activity and reduced acute and chronic inflammation^[42]. In addition to turmeric, rosemary oil also protects the liver.

Liver Protection Essential Oil #4: Rosemary Essential Oil
Rosemary essential oil demonstrated liver protecting properties by reversing  chemical injury to antioxidant enzymes catalase, peroxidase, glutathione peroxidase and glutathione reductase in a rat study^[43]. This oil also demonstrated liver protecting properties in a separate mouse study^[44]. In another lab study, rosemary oil inhibited the proliferation of human liver carcinoma cells^[45]. In another mouse study, rosemary oil reduced the inflammatory compound IL-6^[46]. In a human study, this oil lowered salivary cortisol levels^[47].

Given that some varieties of rosemary essential oil have high camphor content which is neurotoxic, rosemary oil (β-myrcene CT) chemotype is recommended because it contains the lowest amount (2.1–4.4%) of this component^[48]. Multiple oils can provide liver protection and can help reduce toxicity and inflammation in patients with Lyme disease and co-infections.

Essential oils that protect the liver can help reduce inflammation in people with Lyme disease
Just like using an insulated oven mitt to get a hot pie out of the oven, anti-toxin and anti-inflammatory essential oils can help people with Lyme and co-infections to protect their liver. These oils can be helpful especially when liver function is damaged by toxins or antibiotics. When encapsulated into a sunflower lecithin liposome and combined with a licorice extract, these oils may be capable of even greater penetration into and protection for the liver. In addition to reducing toxicity, these oils may also help with relieving painful emotions that are associated with liver dysfunction. Since some of these essential oils have cautions on their use, work with a Lyme literate essential oil practitioner to develop a proper, safe, and effective strategy for your condition.

– Greg

>> Next step: Click here to take our Stealthy Co-infection Quiz to see which tick infections may be causing your symptoms.


P.S. Do you have experiences where remedies, or treatments helped to protect your liver, reduce toxins, and lift depression? Tell us about it.

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^[2] Kłuciński, P., A. Maślankiewicz, and M. Ograbek. “[Difficulties in diagnosis of lyme borreliosis].” Przegla̧d Epidemiologiczny 51, no. 4 (1997): 441–44. https://www.ncbi.nlm.nih.gov/pubmed/9562793

^[3] Dadamessi, I., F. Brazier, A. Smaïl, R. Delcenserie, J. L. Dupas, and J. P. Capron. “[Hepatic disorders related to Lyme disease. Study of two cases and a review of the literature].” Gastroentérologie Clinique Et Biologique 25, no. 2 (February 2001): 193–96. https://www.ncbi.nlm.nih.gov/pubmed/11319444

^[4] Ilowite, N. T. “Muscle, Reticuloendothelial, and Late Skin Manifestations of Lyme Disease.” The American Journal of Medicine 98, no. 4A (April 24, 1995): 63S – 68S. https://www.ncbi.nlm.nih.gov/pubmed/7726194

^[5] Saz, J. V., S. Nuncio, F. J. Merino, M. Aquise, J. Medina, and A. R. Filipe. “[Lyme disease in the province of Soria: clinico-epidemiologic study].” Enfermedades Infecciosas Y Microbiología Clínica 12, no. 2 (February 1994): 52–59. https://www.ncbi.nlm.nih.gov/pubmed/8011711

^[6] Benedix, Frauke, Benjamin Weide, Sigrid Broekaert, Gisela Metzler, Julia-Stefanie Frick, Walter H. C. Burgdorf, Martin Röcken, and Martin Schaller. “Early Disseminated Borreliosis with Multiple Erythema Migrans and Elevated Liver Enzymes: Case Report and Literature Review.” Acta Dermato-Venereologica 87, no. 5 (2007): 418–21. doi:10.2340/00015555-0267. https://www.ncbi.nlm.nih.gov/pubmed/17721649

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^[8] Pasta, Linda, and Francesca Pasta. “PAI-1 4G-4G and MTHFR 677TT in Non-Hepatitis C Virus/hepatitis B Virus-Related Liver Cirrhosis.” World Journal of Hepatology 7, no. 29 (December 18, 2015): 2920–26. doi:10.4254/wjh.v7.i29.2920. https://www.ncbi.nlm.nih.gov/pubmed/26689658

^[9] Kasapoglu, Benan, Cansel Turkay, Kadir Serkan Yalcin, Ali Kosar, and Alper Bozkurt. “MTHFR 677C/T and 1298A/C Mutations and Non-Alcoholic Fatty Liver Disease.” Clinical Medicine (London, England) 15, no. 3 (June 2015): 248–51. doi:10.7861/clinmedicine.15-3-248. https://www.ncbi.nlm.nih.gov/pubmed/26031974

^[10] Qi, Xiaosheng, Xing Sun, Junming Xu, Zhaowen Wang, Jinyan Zhang, and Zhihai Peng. “Associations between Methylenetetrahydrofolate Reductase Polymorphisms and Hepatocellular Carcinoma Risk in Chinese Population.” Tumour Biology: The Journal of the International Society for Oncodevelopmental Biology and Medicine 35, no. 3 (March 2014): 1757–62. doi:10.1007/s13277-013-1529-x. https://www.ncbi.nlm.nih.gov/pubmed/24385382

^[11] Singla, Neha, Dheeraj Gupta, Niti Birbian, and Jagtar Singh. “Association of NAT2, GST and CYP2E1 Polymorphisms and Anti-Tuberculosis Drug-Induced Hepatotoxicity.” Tuberculosis (Edinburgh, Scotland) 94, no. 3 (May 2014): 293–98. doi:10.1016/j.tube.2014.02.003. https://www.ncbi.nlm.nih.gov/pubmed/24637014

^[12] Horowitz, H. W., B. Dworkin, G. Forseter, R. B. Nadelman, C. Connolly, B. B. Luciano, J. Nowakowski, T. A. O’Brien, M. Calmann, and G. P. Wormser. “Liver Function in Early Lyme Disease.” Hepatology (Baltimore, Md.) 23, no. 6 (June 1996): 1412–17. doi:10.1002/hep.510230617.

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^[16] Chan, S. S., Y. C. Wong, and I. J. Hodgkiss. “A Preliminary Study of C-Reactive Protein in the Diagnosis and Monitoring of Lyme Disease.” Biomedical and Environmental Sciences: BES 9, no. 4 (December 1996): 424–29. https://www.ncbi.nlm.nih.gov/pubmed/8988812

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^[25] Podobed, O. V., L. M. Fedorova, O. Iu Abakumova, I. V. Iakusheva, T. A. Tsvetkova, A. V. Gavril’chak, A. B. Shekhter, and A. V. Kariakin. “[A study of hepatoprotective effect of the preparation phospholiv containing phosphatidylcholine from sunflower seeds and glycyrrhizic acid in the model of liver cirrhosis in rats].” Biulleten’ Eksperimental’noĭ Biologii I Meditsiny 124, no. 9 (September 1997): 311–14. https://www.ncbi.nlm.nih.gov/pubmed/9445615

^[26] Elmowafy, Mohammed, Tapani Viitala, Hany M. Ibrahim, Sherif K. Abu-Elyazid, Ahmed Samy, Alaa Kassem, and Marjo Yliperttula. “Silymarin Loaded Liposomes for Hepatic Targeting: In Vitro Evaluation and HepG2 Drug Uptake.” European Journal of Pharmaceutical Sciences: Official Journal of the European Federation for Pharmaceutical Sciences 50, no. 2 (October 9, 2013): 161–71. doi:10.1016/j.ejps.2013.06.012. https://www.ncbi.nlm.nih.gov/pubmed/23851081

^[27] Sultan, Muhammad Tauseef, Masood Sadiq Butt, Roselina Karim, Shahzad Zafar Iqbal, Shakeel Ahmad, Muhammad Zia-Ul-Haq, Luigi Aliberti, Atif Nisar Ahmad, and Vincenzo De Feo. “Effect of Nigella Sativa Fixed and Essential Oils on Antioxidant Status, Hepatic Enzymes, and Immunity in Streptozotocin Induced Diabetes Mellitus.” BMC Complementary and Alternative Medicine 14 (2014): 193. doi:10.1186/1472-6882-14-193. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077235/

^[28] Tekeoglu, Ibrahim, Ali Dogan, Levent Ediz, Mustafa Budancamanak, and Adnan Demirel. “Effects of Thymoquinone (volatile Oil of Black Cumin) on Rheumatoid Arthritis in Rat Models.” Phytotherapy Research: PTR 21, no. 9 (September 2007): 895–97. doi:10.1002/ptr.2143.  https://www.ncbi.nlm.nih.gov/pubmed/17562570

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^[30] Ahmad, Aftab, Asif Husain, Mohd Mujeeb, Shah Alam Khan, Abul Kalam Najmi, Nasir Ali Siddique, Zoheir A. Damanhouri, and Firoz Anwar. “A Review on Therapeutic Potential of Nigella Sativa: A Miracle Herb.” Asian Pacific Journal of Tropical Biomedicine 3, no. 5 (May 2013): 337–52. doi:10.1016/S2221-1691(13)60075-1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642442/

^[31] Perveen, Tahira, Saida Haider, Sumera Kanwal, and Darakhshan Jabeen Haleem. “Repeated Administration of Nigella Sativa Decreases 5-HT Turnover and Produces Anxiolytic Effects in Rats.” Pakistan Journal of Pharmaceutical Sciences 22, no. 2 (April 2009): 139–44. https://www.ncbi.nlm.nih.gov/pubmed/19339222

^[32] Perveen, Tahira, Saida Haider, Nudrat Anwar Zuberi, Sadia Saleem, Sana Sadaf, and Zehra Batool. “Increased 5-HT Levels Following Repeated Administration of Nigella Sativa L. (Black Seed) Oil Produce Antidepressant Effects in Rats.” Scientia Pharmaceutica 82, no. 1 (March 2014): 161–70. doi:10.3797/scipharm.1304-19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951226/

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^[48] Essential Oil Safety: A Guide for Health Care Professionals-, 2e. 2 edition. Edinburgh: Churchill Livingstone, 2013. pp. 1783-1795.

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Getting Rid of Lyme Disease Evening Talk
in Frederick, Maryland

Monday February 1st from 6pm – 9pm
10 N. Jefferson Street, Suite 203,
Frederick, MD 21701

People with Lyme disease can still be sick with pain, fatigue,
or neurological problems despite months or years of treatment.

Why are some Lyme patients sick despite many years of antibiotics?

What else besides medications will help them to clear their infections?

Which detoxification methods are helping people to heal their Lyme disease?

Monday February 1st, 6:00 pm – 9:00 pm
Location: Two Frogs Healing Center, 10 N. Jefferson Street, Suite 203, Frederick, MD
Evening lecture tuition: $20
Click here to register: https://goodbyelyme.com/events/get_rid_lyme

Deer, mice, birds, and squirrels carry infected ticks into suburban
neighborhoods
These ticks that can carry Lyme and over 60 other tick infections that can make
diagnosis and treatment much more lengthy and complicated. Lyme disease has
also been reported in chiggers, mosquitoes, and biting flies.

Lyme bacteria can be very hard to eliminate from your system
Ticks can infect people without leaving a rash. The Lyme bacteria can hide in
their joints and in their nervous system. They produce lots of toxins that quickly
erase the benefits of treatment.

The Lyme bacteria can lay dormant under a protective slime called a biofilm
Alternative medicines cut through slime, remove toxins and kill bacteria
Ayurvedic and Chinese herbs have been scientifically proven to cut through
bacteria biofilms. When patients take anti-toxin and anti-Lyme herbs, they
report recovering 80% – 100% off their energy, getting their mental clarity
back, and being pain-free for the first time in years.

AJ received an electrodermal scan which showed elevated levels of Epstein-Barr
and Cytomegalovirus, mycoplasma, and a Lyme disease infection. She also tested
positive for the MTHFR and BHMT genetic mutations that affect detoxification
through the methylation cycle.

She was treated with Frequency Specific Microcurrent, nascent iodine, and
liposomal herbs and essential oils for gut repair, Lyme disease, mycoplasma,
and viruses. She also received cupping and bloodletting to pull out toxins and
inflammation out of her nervous system. After a few treatments, her gut was
much less bloated, energy levels were 90% better, and joint pains were almost
entirely gone. She felt so much better that she planned a vacation for the first
time in three years. How is this possible?

Learn how the latest natural treatments can help to relieve persistent Lyme
disease symptoms of dizziness, gut problems, and fatigue. Also learn how
remedies help with treating co-infections, restoring energy, and relieving
brain inflammation.

To reserve your space please click on
https://goodbyelyme.com/events/get_rid_lyme
or for more information call us at 301.228.3764 .

Learn to Reduce Recurring Symptoms Faster in Your Lyme Disease Patients Through Essential Oils

-Do you have Lyme patients that continue to report recurring
pain, fatigue and mental fog?

– Are you frustrated by the lack of patient improvement with
Lyme protocols?

– Learn about safe amounts of essential oils for internal use
to treat stubborn Lyme symptoms.

– Receive a free subscription to our GoodbyeLyme Newsletter
(we don’t share your info with anyone).

Get two chances on the webinar to win a cold
laser and a test kit!
Participants that join early will have a chance to win
a cold laser and an essential oil remedy test kit for Lyme
and other infections worth $100. You need to be on the
video link to qualify for the bonus. You can listen over
the phone, however you will not be qualified to receive
the bonuses (phone listeners do not have an option to
use the chat function).

Towards the end of the webinar, there will be another
chance to win a second laser and test kit. This laser
and test kit are the actual equipment that I use in the
treatment room with patients. If you are a winner, then
please private message us in the chat with your email or
phone number so we can contact you to get your mailing
address.

Get awesome information in one training for only ($22) 1x time Live Online Training
(A link to the training will be sent to the email that you submit via Paypal)

Register at this link:
https://unbouncepages.com/internal-essential-oils-for-lyme-symptoms/

You will receive in your inbox a unique link to join the
training. This link is unique to your email that you used
to register so please don’t share it or you won’t be able
to get on. Space is limited…

See you on the training!

– Greg

Greg Lee is a world expert on using Chinese herbs, essential oils and natural treatments for healing incredibly persistent Lyme disease. He has developed special methods for customizing and delivering essential oils to help patients heal their stubborn, chronic infections.

Hey it’s Greg here,

If you are at all interested in learning
how to use essential oils, then I highly
recommend getting the book:

Essential Oil Safety, 2nd Ed.

https://digitalsoftocean.com/product/essential-oil-safety-a-guide-for-health-care-professionals-2e/

The hardcover is around $80, for the next
hour you can get a digital copy for $13.
I’m not making any commission on the sale,

Robert Tisserand’s work is extremely
valuable to helping me formulate
essential oils safely for my patients.
He provides topical and internal dosing
guidelines based on human and animal
studies.

I just downloaded my copy and I’m able to
search through and find what I want to know
about individual oils more quickly.

Don’t delay because there is only a short
amount of time left to get this offer.

Peace and healing,

Greg

P.S. Interested in learning how to stop recurring
Lyme symptoms using essential oils?
https://goodbyelyme.com/training

For people with tremors that have been exposed to toxic mold
by Greg Lee

I’ve enjoyed going on hikes with a friend and his dog. This dog loves to go into the water and then run up and shake water all over you. We quickly learned to run away as soon as the dog would come out of the water. Of course, the dog would chase us down and still managed to shake water all over us.

How is a wet-shaking dog similar to a person with tremors from mold toxins?

Just like a dog that instinctively shakes water off, tremors can be a sign of exposure to mold toxins
In multiple animal studies, toxins from mold have produced tremors in dogs^[1], mice^[2], horses^[3], cattle^[4], sheep^[5], and rabbits^[6]. These toxins have weird names like: Aflatoxins^[7], penitrem A, thomitrem A and E^[8], lolitrem B^[9], and roquefortine C^[10]. Animals have usually ingested these toxins through eating moldy food or plants. Tremors have been found to range from mild to life-threatening in these studies. In one study, cattle developed degeneration of motor neurons in the midbrain, brain stem and spinal cord^[11]. Rapid diagnosis and treatment usually results in a complete resolution of tremors. Not only can animals get tremors from mold toxins, so can people.

People can be more susceptible to mold toxins than animals
Because of their improved ability to detoxify mycotoxins (fungal toxins), livestock animals are more resistant to mold toxins than people^[12]. The most likely sources for people of “tremorgenic” mycotoxins, i.e. toxins that produce tremors, are contaminated food and mold from water damaged buildings. In a couple of studies, people that have ingested^[13] or been exposed to environmental mold toxins^[14] developed significant symptoms. In the study on exposure to environmental mold, the person also developed dementia. After several days, the tremor symptoms resolved fully. People can have genetic variations which limit their ability to detoxify mold toxins.

Human Leukocyte Antigen (HLA) genes can limit a person’s mycotoxin detoxification abilities
People get a set of HLA genes from each of their parents. These genes determine which kinds of toxins you can identify and eliminate^[15]. Approximately, 25% of the population have HLA types which limit their ability to detoxify biotoxins. Often the sickest people that have been exposed to mold have HLA types which limit how they can eliminate those toxins^[16]. Not only can people ingest toxins, they can also become infected by mold.

Many different types of toxic fungi have been known to infect people and produce severe symptoms
Many different kinds of toxic mold have been found to infect people often who are immune compromised with an infection or an autoimmune illness or after an organ transplant. In different studies, multiple fungi have been found to infect the brain^[17], lungs^[18], gut^[19], kidneys^[20], mucus membranes^[21], sinuses, liver, heart, blood vessels, bones^[22], and skin^[23]. Some Fusarium mycotoxins make animals more susceptible to infections and possibly people, too^[24]. In addition to tremors, emotional symptoms of anxiety, depression, and cognitive difficulties are often reported by patients^[25]. Unfortunately, drug resistant fungal infections are becoming more prevalent.

Drug resistant fungal infections are showing up in research findings
Drug resistant forms of these infectious fungi have been discovered including: Aspergillus^[26], Fusarium^[27], Candida^[28], Scedosporium, Mucorales, and Penicillium^[29]. Several fungal infections have the ability to produce biofilms to protect themselves against medications^[30]. Fungal biofilms are estimated to increase drug resistance to anti-fungal medications as much at 1000 fold^[31].

What can help patients that have genetic limitations with eliminating toxins to overcome drug-resistant, tremor-toxic fungal infections?

Here are four essential oils that are effective at fighting mold infections and their tremor-toxins
Fortunately, there are essential oils that inhibit the growth and toxin production of toxic mold in lab and animal studies. Preparing the oils in a micronized form called a liposome, which are microscopic particles of medicinal oils that are wrapped in a fat called lecithin, would increase their penetration into affected tissues and organs. Liposomal anti-fungal medications have been more effective at inhibiting pathogenic fungi^[32] and penetrating fungal biofilms^[33]. Which is why liposomal essential oils maybe more effective at helping patients with tremors induced by a tremor-toxic fungal infection.

Anti-tremor Liposomal Essential Oil #1: Cinnamon bark, Chinese name: Rou Gui
In Chinese medicine, “Internal Wind” is described as a primary factor which creates tremors in patients^[34]. Fortunately, cinnamon essential oil is used in Chinese medicine to “expel Wind” in patients. (In the west, expelling wind means something totally different. 🙂 In Chinese medicine, it is a real diagnosis, not a joke). This oil is also used to clear dampness, invigorate the blood, treat parasites, increase energy (Qi), and warm coldness^[35]. Dampness can refer to signs of infection like swelling, discharge, leakage, or mental unclarity. This oil is cautioned in patients with heat signs, and in pregnancy.

In lab studies, cinnamon essential oil was most effective against fluconazole-resistant Candida glabrata^[36] and Fusarium keratitis^[37]. It also protects against the growth of Aspergillus species^[38] and mycotoxin development^[39], and inhibits the growth of Fusarium mycotoxins^[40]. In addition to cinnamon bark, German chamomile may help with calming tremors by reducing Wind.

Anti-tremor Liposomal Essential Oil #2: German chamomile
In Chinese medicine, one of the reasons why tremors arise from “Liver Wind” is due to dryness and heat in the Liver^[41]. German chamomile subdues wind, calms the heart spirit (shen), clears heat in the Liver, Stomach, Heart. This essential oil also drains “dampness.” German chamomile also nourishes the yin of the Heart, smooths Liver Qi and Spleen Qi, and increases Lung Qi^[42].

In lab studies, German chamomile inhibits Aspergillus niger^[43], and mycotoxin production by Aspergillus parasiticus and Fusarium graminearum^[44]. In one study, this oil has anti-inflammatory properties and is used to relieve migraines^[45]. In another lab study, this oil inhibited cancer cell growth, and demonstrated anti-allergic, and antioxidant properties^[46]. In a small human study, German chamomile helped relieve depression through its action as a serotonin and noradrenaline re-uptake inhibitor^[47]. In addition to German chamomile, clary sage also decreases Wind.

Anti-tremor Liposomal Essential Oil #3: Clary sage
Clary sage essential oil subdues wind, clears heat from the stomach, cools the blood, nourishes yin, smooths Liver Qi, Spleen Qi, strengthens Heart and Lung Qi, clears empty heat, encourages labor, regulates the menses, treats diarrhea. This oil is cautioned in people with cancer, and pregnancy. Since it can be narcotic in large doses, it is cautioned in people who are consuming alcohol. It also has estrogenic properties^[48].

When combined with juniper essential oil, clary sage oil was effective against multiple strains of yeast in one lab study^[49]. In a wound healing study, clary sage oil was effective against strains of antibiotic resistant bacteria isolated from patients^[50]. In a study with menopausal women, this oil reduced cortisol levels, increased 5HTP levels, and had an antidepressant like effect^[51]. Lemongrass oil has demonstrated broad anti-fungal effects in multiple studies.

Anti-tremor Liposomal Essential Oil #4: Lemongrass essential oil
The properties of lemongrass oil are nourishing blood, strengthen Spleen Qi, tonify yang energy, warm interior to expel cold, and strengthen defensive energy (Wei Qi). This oil is cautioned in patients with heat signs, glaucoma, prostatic hyperplasia, and in children^[52].

Lemongrass has inhibited Candida and Aspergillus in a lab study^[53]. In another study, lemongrass oil inhibited three different fungal species^[54]. This oil also inhibited the mycotoxin production and growth of multiple Aspergillus species in a third study^[55]. In multiple mouse studies^[56], lemongrass oil reduced anxiety behaviors^[57]. A combination of liposomal essential oils can help to relieve the underlying causes of Wind induced tremors.

Essential oils that reduce Wind can help relieve tremors from a toxic mold exposure
Just like a dog that shakes off excess water, anti-Wind and anti-fungal essential oils can help toxic mold patients to shake off Wind induced tremors. In addition to reducing tremors, these oils can help with relieving accompanying symptoms of depression and anxiety. Giving the oils in a liposomal mixture increases the likelihood of inhibiting fungi, tremorgenic toxins, and penetrating fungal biofilms. Since some of these essential oils have cautions on their use, work with a mold literate essential oil practitioner to develop a proper, safe, and effective strategy for your condition.

– Greg

>> Next step: Click here to take our What Lyme Brain Type are You? Quiz to help identify underlying causes of neurological Lyme.


P.S. Do you have experiences where remedies, or treatments helped to quiet tremors caused by toxic mold? Tell us about it.

^[1] Barker, Andrew K., Chase Stahl, Steve M. Ensley, and Nick D. Jeffery. “Tremorgenic Mycotoxicosis in Dogs.” Compendium (Yardley, PA) 35, no. 2 (February 2013): E2. https://www.ncbi.nlm.nih.gov/pubmed/23532902

^[2] Moldes-Anaya, Angel, Thomas Rundberget, Christiane K. Fæste, Gunnar S. Eriksen, and Aksel Bernhoft. “Neurotoxicity of Penicillium Crustosum Secondary Metabolites: Tremorgenic Activity of Orally Administered Penitrem A and Thomitrem A and E in Mice.” Toxicon: Official Journal of the International Society on Toxinology 60, no. 8 (December 15, 2012): 1428–35. doi:10.1016/j.toxicon.2012.10.007. https://www.ncbi.nlm.nih.gov/pubmed/23085423

^[3] Johnstone, L. K., I. G. Mayhew, and L. R. Fletcher. “Clinical Expression of Lolitrem B (perennial Ryegrass) Intoxication in Horses.” Equine Veterinary Journal 44, no. 3 (May 2012): 304–9. doi:10.1111/j.2042-3306.2011.00439.x. https://www.ncbi.nlm.nih.gov/pubmed/21793878

^[4] Uhlig, Silvio, Christo J. Botha, Trude Vrålstad, Elin Rolén, and Christopher O. Miles. “Indole-Diterpenes and Ergot Alkaloids in Cynodon Dactylon (Bermuda Grass) Infected with Claviceps Cynodontis from an Outbreak of Tremors in Cattle.” Journal of Agricultural and Food Chemistry 57, no. 23 (December 9, 2009): 11112–19. doi:10.1021/jf902208w. https://www.ncbi.nlm.nih.gov/pubmed/19891432

^[5] Smith, B. L., L. M. McLeay, and P. P. Embling. “Effect of the Mycotoxins Penitrem, Paxilline and Lolitrem B on the Electromyographic Activity of Skeletal and Gastrointestinal Smooth Muscle of Sheep.” Research in Veterinary Science 62, no. 2 (April 1997): 111–16. https://www.ncbi.nlm.nih.gov/pubmed/9243707

^[6] Nishiyama, M., and T. Kuga. “Pharmacological Effects of the Tremorgenic Mycotoxin Fumitremorgin A.” Japanese Journal of Pharmacology 40, no. 4 (April 1986): 481–89. https://www.ncbi.nlm.nih.gov/pubmed/3735799

^[7] Caloni, Francesca, and Cristina Cortinovis. “Toxicological Effects of Aflatoxins in Horses.” Veterinary Journal (London, England: 1997) 188, no. 3 (June 2011): 270–73. doi:10.1016/j.tvjl.2010.06.002. https://www.ncbi.nlm.nih.gov/pubmed/20619706

^[8] Moldes-Anaya, Angel, Thomas Rundberget, Christiane K. Fæste, Gunnar S. Eriksen, and Aksel Bernhoft. “Neurotoxicity of Penicillium Crustosum Secondary Metabolites: Tremorgenic Activity of Orally Administered Penitrem A and Thomitrem A and E in Mice.” Toxicon: Official Journal of the International Society on Toxinology 60, no. 8 (December 15, 2012): 1428–35. doi:10.1016/j.toxicon.2012.10.007.

^[9] Johnstone, L. K., I. G. Mayhew, and L. R. Fletcher. “Clinical Expression of Lolitrem B (perennial Ryegrass) Intoxication in Horses.” Equine Veterinary Journal 44, no. 3 (May 2012): 304–9. doi:10.1111/j.2042-3306.2011.00439.x. https://www.ncbi.nlm.nih.gov/pubmed/21793878

^[10] Eriksen, G. S., K. Hultin Jäderlund, A. Moldes-Anaya, J. Schönheit, A. Bernhoft, G. Jaeger, T. Rundberget, and I. Skaar. “Poisoning of Dogs with Tremorgenic Penicillium Toxins.” Medical Mycology 48, no. 1 (February 2010): 188–96. doi:10.3109/13693780903225821. https://www.ncbi.nlm.nih.gov/pubmed/19886763

^[11] Niederberger, M., A. Oevermann, F. Kirscher, and M. Meylan. “[Tremorgenic syndrome in a cattle herd after feeding silage contaminated with A. clavatus].” Schweizer Archiv Für Tierheilkunde 153, no. 3 (March 2011): 105–10. doi:10.1024/0036-7281/a000163. https://www.ncbi.nlm.nih.gov/pubmed/21360447

^[12] Hussein, H. S., and J. M. Brasel. “Toxicity, Metabolism, and Impact of Mycotoxins on Humans and Animals.” Toxicology 167, no. 2 (October 15, 2001): 101–34. https://www.ncbi.nlm.nih.gov/pubmed/11567776

^[13] Lewis, Peter R., Michael B. Donoghue, Ailsa D. Hocking, Lucy Cook, and Linda V. Granger. “Tremor Syndrome Associated with a Fungal Toxin: Sequelae of Food Contamination.” The Medical Journal of Australia 182, no. 11 (June 6, 2005): 582–84. https://www.ncbi.nlm.nih.gov/pubmed/15938687

^[14] Gordon, K. E., R. E. Masotti, and W. R. Waddell. “Tremorgenic Encephalopathy: A Role of Mycotoxins in the Production of CNS Disease in Humans?” The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques 20, no. 3 (August 1993): 237–39. https://www.ncbi.nlm.nih.gov/pubmed/8221391

^[15] Shoemake, R. The Biotoxin Pathway.  https://www.survivingmold.com/diagnosis/the-biotoxin-pathway

^[16] Shoemake, R. What is Mold Illness? Better yet, do people get sick after being exposed to water-damaged buildings? https://www.survivingmold.com/diagnosis

^[17] Beraldo, Daniel, Ramon Guerra, Vinícius Alvarenga, and Letícia Crepaldi. “Surgical Treatment Alone of Cerebral Aspergillosis in Immunocompetent Patient.” Journal of Neurological Surgery. Part A, Central European Neurosurgery, August 3, 2015. doi:10.1055/s-0035-1558415.

https://www.ncbi.nlm.nih.gov/pubmed/26238939

^[18] Osmanov, Ali, and David W. Denning. “Burden of Serious Fungal Infections in Ukraine.” Mycoses 58 Suppl 5 (October 2015): 94–100. doi:10.1111/myc.12409. https://www.ncbi.nlm.nih.gov/pubmed/26449513

^[19] Li, Elizabeth, Hayder Hussein, Adil Todiwala, and Robert Kirby. “Primary Gut Aspergillosis in a Patient with Acute Myeloid Leukaemia: The Importance of Early Suspicion and Definitive Treatment.” BMJ Case Reports 2014 (2014). doi:10.1136/bcr-2013-202316. https://www.ncbi.nlm.nih.gov/pubmed/24642177

^[20] Meng, Xiao-Chun, Ting Jiang, Shu-Hong Yi, Pei-Yi Xie, Yue-Fei Guo, Li Quan, Jing Zhou, Kang-Shun Zhu, and Hong Shan. “Renal Aspergillosis after Liver Transplantation: Clinical and Imaging Manifestations in Two Cases.” World Journal of Gastroenterology 20, no. 48 (December 28, 2014): 18495–502. doi:10.3748/wjg.v20.i48.18495. https://www.ncbi.nlm.nih.gov/pubmed/25561822

^[21] Nett, Jeniel E., and David R. Andes. “Fungal Biofilms: In Vivo Models for Discovery of Anti-Biofilm Drugs.” Microbiology Spectrum 3, no. 3 (June 2015). https://www.ncbi.nlm.nih.gov/pubmed/26397003

^[22] Walsh, Thomas J., and Dennis M. Dixon. “Spectrum of Mycoses.” In Medical Microbiology, edited by Samuel Baron, 4th ed. Galveston (TX): University of Texas Medical Branch at Galveston, 1996. https://www.ncbi.nlm.nih.gov/books/NBK7902/.

^[23] Tessari, G., A. Cagalli, and G. Girolomoni. “Opportunistic Deep Cutaneous Mycoses in Solid Organ Transplant Recipients.” Giornale Italiano Di Dermatologia E Venereologia: Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia 149, no. 4 (August 2014): 417–22. https://www.ncbi.nlm.nih.gov/pubmed/25068229

^[24] Antonissen, Gunther, An Martel, Frank Pasmans, Richard Ducatelle, Elin Verbrugghe, Virginie Vandenbroucke, Shaoji Li, Freddy Haesebrouck, Filip Van Immerseel, and Siska Croubels. “The Impact of Fusarium Mycotoxins on Human and Animal Host Susceptibility to Infectious Diseases.” Toxins 6, no. 2 (February 2014): 430–52. doi:10.3390/toxins6020430. https://www.ncbi.nlm.nih.gov/pubmed/24476707

^[25] Louis, Elan D. “Non-Motor Symptoms in Essential Tremor: A Review of the Current Data and State of the Field.” Parkinsonism & Related Disorders, August 29, 2015. doi:10.1016/j.parkreldis.2015.08.034. https://www.ncbi.nlm.nih.gov/pubmed/26343494

^[26] Mousavi, Bita, Mohammad T. Hedayati, Ladan Teimoori-Toolabi, Jacques Guillot, Ahad Alizadeh, and Hamid Badali. “cyp51A Gene Silencing Using RNA Interference in Azole-Resistant Aspergillus Fumigatus.” Mycoses, October 8, 2015. doi:10.1111/myc.12417. https://www.ncbi.nlm.nih.gov/pubmed/26448519

^[27] Kandeel, Ahmed, Kareem Abu-Elmagd, Michael Spinner, Ajai Khanna, Koji Hashimoto, Masato Fujiki, Mansiur Parsi, Ana Bennett, Galal El-Gazzaz, and Ahmed Abd-Elaal. “Atypical Clinical Presentation of a Newer Generation Anti-Fungal Drug-Resistant Fusarium Infection After a Modified Multi-Visceral Transplant.” Annals of Transplantation: Quarterly of the Polish Transplantation Society 20 (2015): 512–18. doi:10.12659/AOT.892209. https://www.ncbi.nlm.nih.gov/pubmed/26334671

^[28] Perlin, David S., Erika Shor, and Yanan Zhao. “Update on Antifungal Drug Resistance.” Current Clinical Microbiology Reports 2, no. 2 (June 1, 2015): 84–95. doi:10.1007/s40588-015-0015-1. https://www.ncbi.nlm.nih.gov/pubmed/26120512

^[29] Alastruey-Izquierdo, A., E. Mellado, T. Peláez, J. Pemán, S. Zapico, M. Alvarez, J. L. Rodríguez-Tudela, M. Cuenca-Estrella, and FILPOP Study Group. “Population-Based Survey of Filamentous Fungi and Antifungal Resistance in Spain (FILPOP Study).” Antimicrobial Agents and Chemotherapy 57, no. 7 (July 2013): 3380–87. doi:10.1128/AAC.00383-13. https://www.ncbi.nlm.nih.gov/pubmed/23669377

^[30] Nett, Jeniel E., and David R. Andes. “Fungal Biofilms: In Vivo Models for Discovery of Anti-Biofilm Drugs.” Microbiology Spectrum 3, no. 3 (June 2015). https://www.ncbi.nlm.nih.gov/pubmed/26397003

^[31] Ramage, Gordon, Ranjith Rajendran, Leighann Sherry, Craig Williams, Gordon Ramage, Ranjith Rajendran, Leighann Sherry, and Craig Williams. “Fungal Biofilm Resistance, Fungal Biofilm Resistance.” International Journal of Microbiology, International Journal of Microbiology 2012, 2012 (February 8, 2012): e528521. doi:10.1155/2012/528521, 10.1155/2012/528521. https://www.hindawi.com/journals/ijmicro/2012/528521/

^[32] Carrillo-Muñoz, A. J., G. Quindós, C. Tur, M. T. Ruesga, Y. Miranda, O. del Valle, P. A. Cossum, and T. L. Wallace. “In-Vitro Antifungal Activity of Liposomal Nystatin in Comparison with Nystatin, Amphotericin B Cholesteryl Sulphate, Liposomal Amphotericin B, Amphotericin B Lipid Complex, Amphotericin B Desoxycholate, Fluconazole and Itraconazole.” The Journal of Antimicrobial Chemotherapy 44, no. 3 (September 1999): 397–401. https://www.ncbi.nlm.nih.gov/pubmed/10511410

^[33] Kuhn, D. M., T. George, J. Chandra, P. K. Mukherjee, and M. A. Ghannoum. “Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins.” Antimicrobial Agents and Chemotherapy 46, no. 6 (June 2002): 1773–80. https://www.ncbi.nlm.nih.gov/pubmed/12019089

^[34] Dharmananda, S. FENG: The Meaning of Wind in Chinese Medicine with special attention to acupoint fengchi (GB-20). https://www.itmonline.org/articles/feng/feng.htm

^[35] Aldrich, Esther, and Randall Bornemann. Fang Xiang Liao Fa: Essential Oil Analogues of TCM Herbal Formulas. CreateSpace Independent Publishing Platform, 2013. p 41.

^[36] Soares, I. H., É S. Loreto, L. Rossato, D. N. Mario, T. P. Venturini, F. Baldissera, J. M. Santurio, and S. H. Alves. “In Vitro Activity of Essential Oils Extracted from Condiments against Fluconazole-Resistant and -Sensitive Candida Glabrata.” Journal De Mycologie Médicale 25, no. 3 (September 2015): 213–17. doi:10.1016/j.mycmed.2015.06.003. https://www.ncbi.nlm.nih.gov/pubmed/26281965

^[37] Homa, Mónika, Ildikó Pálma Fekete, Andrea Böszörményi, Yendrembam Randhir Babu Singh, Kanesan Panneer Selvam, Coimbatore Subramanian Shobana, Palanisamy Manikandan, László Kredics, Csaba Vágvölgyi, and László Galgóczy. “Antifungal Effect of Essential Oils against Fusarium Keratitis Isolates.” Planta Medica 81, no. 14 (September 2015): 1277–84. doi:10.1055/s-0035-1546272. https://www.ncbi.nlm.nih.gov/pubmed/26227503

^[38] Carmo, Egberto Santos, Edeltrudes de Oliveira Lima, Evandro Leite de Souza, and Frederico Barbosa de Sousa. “Effect of Cinnamomum Zeylanicum Blume Essential Oil on the Growth and Morphogenesis of Some Potentially Pathogenic Aspergillus Species.” Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology] 39, no. 1 (January 2008): 91–97. doi:10.1590/S1517-838220080001000021. https://www.ncbi.nlm.nih.gov/pubmed/24031186

^[39] Soliman, K. M., and R. I. Badeaa. “Effect of Oil Extracted from Some Medicinal Plants on Different Mycotoxigenic Fungi.” Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association 40, no. 11 (November 2002): 1669–75. https://www.ncbi.nlm.nih.gov/pubmed/12176092

^[40] Velluti, A., V. Sanchis, A. J. Ramos, C. Turon, and S. Marín. “Impact of Essential Oils on Growth Rate, Zearalenone and Deoxynivalenol Production by Fusarium Graminearum under Different Temperature and Water Activity Conditions in Maize Grain.” Journal of Applied Microbiology 96, no. 4 (2004): 716–24. https://www.ncbi.nlm.nih.gov/pubmed/15012810

^[41] Dharmananda, S. FENG: The Meaning of Wind in Chinese Medicine with special attention to acupoint fengchi (GB-20). https://www.itmonline.org/articles/feng/feng.htm

^[42] Aldrich, Esther, and Randall Bornemann. Fang Xiang Liao Fa: Essential Oil Analogues of TCM Herbal Formulas. CreateSpace Independent Publishing Platform, 2013. p 43.

^[43] Tolouee, Marziyeh, Soheil Alinezhad, Reza Saberi, Ali Eslamifar, Seyed Javad Zad, Kamkar Jaimand, Jaleh Taeb, et al. “Effect of Matricaria Chamomilla L. Flower Essential Oil on the Growth and Ultrastructure of Aspergillus Niger van Tieghem.” International Journal of Food Microbiology 139, no. 3 (May 15, 2010): 127–33. doi:10.1016/j.ijfoodmicro.2010.03.032. https://www.ncbi.nlm.nih.gov/pubmed/20385420

^[44] Yoshinari, Tomoya, Atsushi Yaguchi, Naoko Takahashi-Ando, Makoto Kimura, Haruo Takahashi, Takashi Nakajima, Yoshiko Sugita-Konishi, Hiromichi Nagasawa, and Shohei Sakuda. “Spiroethers of German Chamomile Inhibit Production of Aflatoxin G and Trichothecene Mycotoxin by Inhibiting Cytochrome P450 Monooxygenases Involved in Their Biosynthesis.” FEMS Microbiology Letters 284, no. 2 (July 2008): 184–90. doi:10.1111/j.1574-6968.2008.01195.x. https://www.ncbi.nlm.nih.gov/pubmed/18492060

^[45] Zargaran, Arman, Afshin Borhani-Haghighi, Pouya Faridi, Saeid Daneshamouz, Gholamreza Kordafshari, and Abdolali Mohagheghzadeh. “Potential Effect and Mechanism of Action of Topical Chamomile (Matricaria Chammomila L.) Oil on Migraine Headache: A Medical Hypothesis.” Medical Hypotheses 83, no. 5 (November 2014): 566–69. doi:10.1016/j.mehy.2014.08.023. https://www.ncbi.nlm.nih.gov/pubmed/25238714

^[46] Mitoshi, Mai, Isoko Kuriyama, Hiroto Nakayama, Hironari Miyazato, Keiichiro Sugimoto, Yuko Kobayashi, Tomoko Jippo, Kazuki Kanazawa, Hiromi Yoshida, and Yoshiyuki Mizushina. “Effects of Essential Oils from Herbal Plants and Citrus Fruits on DNA Polymerase Inhibitory, Cancer Cell Growth Inhibitory, Antiallergic, and Antioxidant Activities.” Journal of Agricultural and Food Chemistry 60, no. 45 (November 14, 2012): 11343–50. doi:10.1021/jf303377f. https://www.ncbi.nlm.nih.gov/pubmed/23088772

^[47] Niederhofer, H. “Observational Study: Matricaria Chamomilla May Improve Some Symptoms of Attention-Deficit Hyperactivity Disorder.” Phytomedicine: International Journal of Phytotherapy and Phytopharmacology 16, no. 4 (April 2009): 284–86. doi:10.1016/j.phymed.2008.10.006. https://www.ncbi.nlm.nih.gov/pubmed/19097772

^[48] Aldrich, Esther, and Randall Bornemann. Fang Xiang Liao Fa: Essential Oil Analogues of TCM Herbal Formulas. CreateSpace Independent Publishing Platform, 2013. p 41.

^[49] Tserennadmid, Rentsenkhand, Miklós Takó, László Galgóczy, Tamás Papp, Miklós Pesti, Csaba Vágvölgyi, Katalin Almássy, and Judit Krisch. “Anti Yeast Activities of Some Essential Oils in Growth Medium, Fruit Juices and Milk.” International Journal of Food Microbiology 144, no. 3 (January 5, 2011): 480–86. doi:10.1016/j.ijfoodmicro.2010.11.004. https://www.ncbi.nlm.nih.gov/pubmed/21131081

^[50] Sienkiewicz, Monika, Anna Głowacka, Katarzyna Poznańska-Kurowska, Andrzej Kaszuba, Anna Urbaniak, and Edward Kowalczyk. “The Effect of Clary Sage Oil on Staphylococci Responsible for Wound Infections.” Postȩpy Dermatologii I Alergologii 32, no. 1 (February 2015): 21–26. doi:10.5114/pdia.2014.40957. https://www.ncbi.nlm.nih.gov/pubmed/25821423

^[51] Lee, Kyung-Bok, Eun Cho, and Young-Sook Kang. “Changes in 5-Hydroxytryptamine and Cortisol Plasma Levels in Menopausal Women after Inhalation of Clary Sage Oil.” Phytotherapy Research: PTR 28, no. 11 (November 2014): 1599–1605. doi:10.1002/ptr.5163. https://www.ncbi.nlm.nih.gov/pubmed/24802524

^[52] Aldrich, Esther, and Randall Bornemann. Fang Xiang Liao Fa: Essential Oil Analogues of TCM Herbal Formulas. CreateSpace Independent Publishing Platform, 2013. https://books.google.com/books/about/Fang_Xiang_Liao_Fa.html. P. 44.

^[53] Boukhatem, Mohamed Nadjib, Mohamed Amine Ferhat, Abdelkrim Kameli, Fairouz Saidi, and Hadjer Tchoketch Kebir. “Lemon Grass (Cymbopogon Citratus) Essential Oil as a Potent Anti-Inflammatory and Antifungal Drugs.” The Libyan Journal of Medicine 9 (2014): 25431. https://www.ncbi.nlm.nih.gov/pubmed/25242268

^[54] Aguiar, Raimundo Wagner de S., Marcio A. Ootani, Sérgio Donizeti Ascencio, Talita P. S. Ferreira, Manoel M. Dos Santos, and Gil R. dos Santos. “Fumigant Antifungal Activity of Corymbia Citriodora and Cymbopogon Nardus Essential Oils and Citronellal against Three Fungal Species.” TheScientificWorldJournal 2014 (2014): 492138. doi:10.1155/2014/492138. https://www.ncbi.nlm.nih.gov/pubmed/24600325

^[55] Sonker, Nivedita, Abhay K. Pandey, Pooja Singh, and N. N. Tripathi. “Assessment of Cymbopogon Citratus (DC.) Stapf Essential Oil as Herbal Preservatives Based on Antifungal, Antiaflatoxin, and Antiochratoxin Activities and in Vivo Efficacy during Storage.” Journal of Food Science 79, no. 4 (April 2014): M628–34. doi:10.1111/1750-3841.12390. https://www.ncbi.nlm.nih.gov/pubmed/24547889

^[56] Costa, Celso A. Rodrigues de Almeida, Daniele Oliveira Kohn, Valéria Martins de Lima, André Costa Gargano, Jorge Camilo Flório, and Mirtes Costa. “The GABAergic System Contributes to the Anxiolytic-like Effect of Essential Oil from Cymbopogon Citratus (lemongrass).” Journal of Ethnopharmacology 137, no. 1 (September 1, 2011): 828–36. doi:10.1016/j.jep.2011.07.003. https://www.ncbi.nlm.nih.gov/pubmed/21767622

^[57] Blanco, M. M., C. a. R. A. Costa, A. O. Freire, J. G. Santos, and M. Costa. “Neurobehavioral Effect of Essential Oil of Cymbopogon Citratus in Mice.” Phytomedicine: International Journal of Phytotherapy and Phytopharmacology 16, no. 2–3 (March 2009): 265–70. doi:10.1016/j.phymed.2007.04.007. https://www.ncbi.nlm.nih.gov/pubmed/17561386

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For people with anxiety, depression, and hopelessness that are diagnosed with Lyme disease and Babesia
by Greg Lee

Have you ever seen a bunch of boys playing football? On weekends, friends and I would play for several hours at my elementary school. After tackling the person with the ball, someone would inevitably yell, “Pile on!!!” And every boy would run and jump onto the boy who got tackled. To the boy at the bottom of the pile, it felt like a super-heavy mass of laughing boys all trying to pin you with their chest and arms.

How is being at the bottom of a pile of boys like a person with Lyme and Babesia anxiety, depression, and hopelessness?

Similar to being at the bottom of the pile, a person with Lyme and Babesia can feel crushed by the weight of their emotions
“My wife thinks I’m crazy.” Phil always woke up wondering if it was going to be a good day or a bad day. A good nights sleep was critical in improving his mood. Some mornings, he felt good enough to get up and go to work. On bad mornings, he felt mired in a dark pit of anxiety, hopelessness, and despair. He hated how he would cry for no reason. Something was eating away at his mind and emotions and taking away any control he had left. Unfortunately, Lyme disease and Babesia toxins can deeply affect your mind and emotions.

Lyme and Babesia produce toxins which can leave a person feeling hopeless and depressed
Unfortunately, there are a limited number of medical providers that really understand how Lyme and Babesia infections can produce states of depression, panic attacks^[1], psychosis^[2], emotional blindness (alexithymia), and suicidal attempts^[3]. Most patients with painful emotions get prescribed antidepressants. These drugs can provide relief in some patients. A subset of these patients do not see improvement in their mood. Unfortunately, antibiotics for Lyme and anti-protozoals for Babesia can also increase painful emotions.

Medications which kill Lyme and Babesia also release endotoxins which can aggravate painful emotions
A Herxheimer reaction or herx occurs when antibiotics kill germs and release toxins that aggravate physical symptoms^[4] as well as uncomfortable emotions. These toxins can wander into all areas of the body. They can affect levels of hormones^[5], neurotransmitters, and inflammatory compounds called cytokines^[6] which can increase anxiety behavior in animal studies^[7]. Unfortunately, Babesia can inhibit the immune system response which allowed greater numbers of Lyme bacteria to flourish in one mouse study^[8].

What can help reverse depression and hopelessness in people with Lyme disease and Babesia?

Here are four remedies for relieving recurring symptoms of hopelessness, depression, and anxiety in Lyme-Babesia patients
Fortunately, there are natural remedies that have anti-spirochete, anti-protozoa, and/or anti-depressive properties in human and animal studies. Babesia is a protozoa infection that is very similar to malaria. Anti-malaria drugs have been shown to reduce Babesia symptoms in patients^[9]. Lyme disease is a spirochete infection which is similar to leptospirosis and syphilis. Anti-leptospirosis antibiotics are also used to treat Lyme disease^[10]. Natural remedies which inhibit leptospirosis have produced significant improvements in symptoms of depression and anxiety in patients with Lyme disease. Phil received a liposomal mixture of herbs and essential oils, which are microscopic particles of these remedies that are wrapped in a fat called lecithin. Liposomes penetrate more deeply into cells than their non-liposomal equivalent medications. Liposomal drugs were 40 times more effective at delivering medicine into and clearing out a malaria infection from red blood cells in a mouse study^[11].

Lyme-Babesia Depression Remedy #1: Bupleurum, Chinese name: Chai Hu
Bupleurum has the properties of bitter, acrid, and cool. It is used to treat Shaoyang syndrome which is described as a pathogenic condition that is unable to be expelled out of the body. This herb is said to be able to guide trapped pathogens out of the body. It used to treat symptoms of alternating fever and chills, fullness and distention of the chest and abdomen, a bitter taste in the mouth, dry throat, poor appetite, nausea and vertigo, and irritability. Bupleurum is also used to treat liver stagnation symptoms including emotional distress, headaches, migraines, eye disorders, breast swelling and pain, irregular menstruation, menstrual cramps, jaundice, and cold extremities. It is also used to treat prolapse of the rectum or uterus, shortness of breath, fatigue, excessive menstruation, and frequent urination. This herb is especially used to treat malaria^[12].

Bupleurum in multiple studies reduces pain, fever, and inflammation. In multiple animal studies, it also protects the liver, increases the production of bile, reduces cholesterol, and stimulates the immune system. This herb has an inhibitory effect on B-hemolytic streptococcus, Vibrio cholerae, Mycobacterium tuberculosis, leptospirosis (a spirochete infection), influenza viruses, and hepatitus viruses Buplerum is cautioned in patients with excessive dryness and heat symptoms. There may an increased risk of acute pneumonitis when this herb is used with interferon^[13]. This herb has demonstrated anti-toxin properties^[14] in multiple animal studies^[15]. Bupleurum reduced depression in one human study by increasing Nerve Growth Factor (NGF) and Brain Derived Neurotrophic Factor (BDNF) in the brain^[16]. Similar to Bupleurum, artemisia has been used to inhibit multiple tick infections.

Lyme-Babesia Depression Remedy #2: Artemisia annua, Chinese name: Qing Hao
Artemisia and two of its derivatives, artemisinin and artesenuate, are being used by physicians to treat patients with Babesia infections. Artemisinin has been used effectively with other medications by a Lyme literate physician to effectively cure persistent, relapsing Babesia^[17].

Artemisia annua has the properties of clears heat, treats malaria, cools the blood, clears liver heat, and brightens the eyes. It is also used to treat “steaming bone disorder” or the feeling that one’s bones are being cooked, tidal fever, unremitting low-grade fever, thirst, soreness and weakness of the low back and knees, irritability, and heat in the palms, soles, and the middle of the chest. Other symptoms this herb is used to treat are warmth at night and chills in the morning, absence of perspiration, heavy limbs, stifling sensation in the chest, and a flushed face. This herb also treats red eyes, dizziness, photophobia, arrhythmia, and jaundice^[18].

Artemisia annua is also effective in inhibiting Staphylococcus aureus (staph), Bacillus anthracis (anthrax), Corynebacterium diphtheriae (diphtheria), Pseudomonas aeruginosa, Bacillus dysenteriae (dysentery), and Mycobacterium tuberculosis (tuberculosis). This herb is cautioned in patients with diarrhea and coldness in the stomach. Azole antifungals and calcium channel blockers may present significant herb-drug interactions with this herb. In long term studies, this herb had no adverse effects on vital organs^[19]. This herb is recommended for treating leptospirosis and Lyme disease in Chinese medicine^[20]. Using the whole herb instead of one derivative compound gives patients the benefits of the synergistic effects of other active compounds. Multiple sesquiterpene and flavonoid compounds from Artemisia annua neutralized the effects of endotoxins in a lab study^[21]. Artemisia annua contains rosmarinic acid which demonstrated a synergistic interaction with artemisinin against the malaria protozoa in a lab study^[22]. Rosmarinic acid also reduced depression^[23] and anxiety behavior^[24] in multiple animal studies. Similar to artemisia, Ylang Ylang essential oil has been used to treat patients with malaria.

Lyme-Babesia Depression Remedy #3: Ylang Ylang essential oil
The properties of this oil are middle note, base note, cooling, calms the spirit and emotions, clears heat, clears heart fire, cools the blood, nourishes yin, nourishes heart, nourishes kidneys, strengthens qi, strengthens kidneys, strengthens wei qi. This oil is cautioned in patients with coldness or yang deficiency^[25].

Traditionally, C. odorata is used to treat malaria, stomach ailments, asthma, gout, and rheumatism. The essential oil or ylang-ylang oil is used in aromatherapy and is believed to be effective in treating depression, high blood pressure, and anxiety. Many phytochemical studies have identified the constituents present in the essential oils of C. odorata. A wide range of chemical compounds including monoterpene, sesquiterpenes, and phenylpropanoids have been isolated from this plant. Recent studies have shown a wide variety of bioactivities exhibited by the essential oils and the extracts of C. odorata including antimicrobial, antibiofilm, anti-inflammatory, antivector, insect-repellent, antidiabetic, antifertility and antimelanogenesis activities^[26]. Just like Ylang Ylang oil, lemongrass essential oil has anti-anxiety properties.

Lyme-Babesia Depression Remedy #4: Lemongrass essential oil
The properties of this oil are top note, nourish blood, strengthen spleen qi, tonify yang energy, warm interior to expel cold, strengthen wei qi. This oil is cautioned in patients with heat signs, glaucoma, prostatic hyperplasia, and in children^[27].

Traditional applications of Cymbopogon genus in different countries shows high applicability as a common tea, medicinal supplement, insect repellent, insecticide, in flu control, and as anti-inflammatory and analgesic. Cymbopogon citratus (lemongrass) is ranked as one of the most widely distributed of the genus which is used in every part of the world. Its applications in Nigeria include cures for upset stomach, malaria therapy, insect repellent and as an antioxidant^[28]. In one lab study, lemongrass essential oil inhibited the malaria parasite^[29]. In multiple mouse studies^[30], lemongrass oil reduced anxiety behaviors^[31]. A combination of remedies with anti-Lyme, anti-Babesia, and mood lifting properties can cut through the dark layers of depression.

Remedies that inhibit Lyme disease, Babesia, and/or depression can help relieve persistent painful emotions
“My wife is really pleased that I’m back to my old self!” Similar to getting out from under a pile of boys, a combination of liposomal anti-Lyme, anti-Babesia remedies can help to fight multiple infections and relieve symptoms of anxiety, hopelessness, and depression. Phil’s liposomal herbs and essential oils helped him to emerge out of his dark pit. He slept better, felt more energized, started to socialize more, and no longer dreaded waking up in the morning. Since some of these remedies have cautions, work with a Lyme literate Chinese medicine practitioner to develop a proper, safe, and effective strategy for your condition.

– Greg

>> Next step: Click here to take our Stealthy Co-infection Quiz to see which tick infections may be causing your symptoms.


P.S. Do you have experiences where  remedies, or treatments helped to lift anxiety, hopelessness, or depression caused by Lyme disease and Babesia? Tell us about it.

^[1] Sherr, V. T. “Panic Attacks May Reveal Previously Unsuspected Chronic Disseminated Lyme Disease.” Journal of Psychiatric Practice 6, no. 6 (November 2000): 352–56. https://www.ncbi.nlm.nih.gov/pubmed/15990495

^[2] Markeljević, Jasenka, Helena Sarac, and Marko Rados. “Tremor, Seizures and Psychosis as Presenting Symptoms in a Patient with Chronic Lyme Neuroborreliosis (LNB).” Collegium Antropologicum 35 Suppl 1 (January 2011): 313–18. https://www.ncbi.nlm.nih.gov/pubmed/21648354

^[3] Banerjee, Rahul, Jerome J. Liu, and Hassan M. Minhas. “Lyme Neuroborreliosis Presenting with Alexithymia and Suicide Attempts.” The Journal of Clinical Psychiatry 74, no. 10 (October 2013): 981. doi:10.4088/JCP.13cr08493. https://www.ncbi.nlm.nih.gov/pubmed/24229748

^[4] Kadam, Pooja, Neal A. Gregory, Bernhard Zelger, and J. Andrew Carlson. “Delayed Onset of the Jarisch-Herxheimer Reaction in Doxycycline-Treated Disease: A Case Report and Review of Its Histopathology and Implications for Pathogenesis.” The American Journal of Dermatopathology 37, no. 6 (June 2015): e68–74. doi:10.1097/DAD.0000000000000093. https://www.ncbi.nlm.nih.gov/pubmed/25033009

^[5] Marre, Meghan L., Courtney T. Darcy, Janeth Yinh, Shizuo Akira, Satoshi Uematsu, Allen C. Steere, and Linden T. Hu. “Role of Adrenomedullin in Lyme Disease.” Infection and Immunity 78, no. 12 (December 2010): 5307–13. doi:10.1128/IAI.00630-10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981333/

^[6] Shaio, M. F., and P. R. Lin. “A Case Study of Cytokine Profiles in Acute Human Babesiosis.” The American Journal of Tropical Medicine and Hygiene 58, no. 3 (March 1, 1998): 335–37. https://www.ajtmh.org/content/58/3/335.full.pdf+html

^[7] Chiu, Gabriel S., Patrick T. Darmody, John P. Walsh, Morgan L. Moon, Kristin A. Kwakwa, Julie K. Bray, Robert H. McCusker, and Gregory G. Freund. “Adenosine through the A2A Adenosine Receptor Increases IL-1β in the Brain Contributing to Anxiety.” Brain, Behavior, and Immunity 41 (October 2014): 218–31. doi:10.1016/j.bbi.2014.05.018. https://www.ncbi.nlm.nih.gov/pubmed/24907587

^[8] Homer, Mary J., Irma Aguilar-Delfin, Sam R. Telford, Peter J. Krause, and David H. Persing. “Babesiosis.” Clinical Microbiology Reviews 13, no. 3 (July 1, 2000): 451–69. doi:10.1128/CMR.13.3.451-469.2000. https://cmr.asm.org/content/13/3/451.full

^[9] Krause, Peter J. “Babesiosis Diagnosis and Treatment.” Vector Borne and Zoonotic Diseases (Larchmont, N.Y.) 3, no. 1 (2003): 45–51. doi:10.1089/153036603765627451. https://www.ncbi.nlm.nih.gov/pubmed/12804380sw`

^[10] Kutsuna, Satoshi, Yasuyuki Kato, Nobuo Koizumi, Kei Yamamoto, Yoshihiro Fujiya, Momoko Mawatari, Nozomi Takeshita, Kayoko Hayakawa, Shuzo Kanagawa, and Norio Ohmagari. “Travel-Related Leptospirosis in Japan: A Report on a Series of Five Imported Cases Diagnosed at the National Center for Global Health and Medicine.” Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy 21, no. 3 (March 2015): 218–23. doi:10.1016/j.jiac.2014.10.004. https://www.ncbi.nlm.nih.gov/pubmed/25459082

^[11] Moles, Ernest, Patricia Urbán, María Belén Jiménez-Díaz, Sara Viera-Morilla, Iñigo Angulo-Barturen, Maria Antònia Busquets, and Xavier Fernàndez-Busquets. “Immunoliposome-Mediated Drug Delivery to Plasmodium-Infected and Non-Infected Red Blood Cells as a Dual Therapeutic/prophylactic Antimalarial Strategy.” Journal of Controlled Release: Official Journal of the Controlled Release Society 210 (May 23, 2015): 217–29. doi:10.1016/j.jconrel.2015.05.284. https://www.ncbi.nlm.nih.gov/pubmed/26008752

^[12] Chen, John K., and Tina T. Chen. 2004. Chinese Medical Herbology and Pharmacology. City of Industry CA: Art of Medicine Press, Inc., pp. 84-87.

^[13] Chen, John K., and Tina T. Chen. 2004. Chinese Medical Herbology and Pharmacology. City of Industry CA: Art of Medicine Press, Inc., pp. 84-87.

^[14] Wu, Jian, Yun-Yi Zhang, Li Guo, Hong Li, and Dao-Feng Chen. “Bupleurum Polysaccharides Attenuates Lipopolysaccharide-Induced Inflammation via Modulating Toll-like Receptor 4 Signaling.” PloS One 8, no. 10 (2013): e78051. doi:10.1371/journal.pone.0078051. https://www.ncbi.nlm.nih.gov/pubmed/24167596

^[15] Xie, Jun-yun, Hong-ye Di, Hong Li, Xiao-qin Cheng, Yun-yi Zhang, and Dao-feng Chen. “Bupleurum Chinense DC Polysaccharides Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Mice.” Phytomedicine: International Journal of Phytotherapy and Phytopharmacology 19, no. 2 (January 15, 2012): 130–37. doi:10.1016/j.phymed.2011.08.057. https://www.ncbi.nlm.nih.gov/pubmed/22112722

^[16] Wang, Xia, Qing Feng, Yong Xiao, and Ping Li. “Radix Bupleuri Ameliorates Depression by Increasing Nerve Growth Factor and Brain-Derived Neurotrophic Factor.” International Journal of Clinical and Experimental Medicine 8, no. 6 (2015): 9205–17. https://www.ncbi.nlm.nih.gov/pubmed/26309578

^[17] Krause, Peter. Panel: Genetic and Acquired Determinants of Host Susceptibility and Vulnerable Populations at the Institute of Medicine of the National Academy of Sciences: A Workshop on the Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-borne Diseases: the Short-Term and Long-Term Outcomes. Washington, DC. October 11, 2010

^[18] Chen, John K., and Tina T. Chen. 2004. Chinese Medical Herbology and Pharmacology. City of Industry CA: Art of Medicine Press, Inc., pp. 244-246.

^[19] Chen, John K., and Tina T. Chen. 2004. Chinese Medical Herbology and Pharmacology. City of Industry CA: Art of Medicine Press, Inc., pp. 244-246.

^[20] Dharmananda, S. Lyme Disease: Treatment with Chinese Herbs https://www.itmonline.org/arts/lyme.htm

^[21] Zhu, Xiaoxin X., Lan Yang, Yujie J. Li, Dong Zhang, Ying Chen, Petra Kostecká, Eva Kmoníčková, and Zdeněk Zídek. “Effects of Sesquiterpene, Flavonoid and Coumarin Types of Compounds from Artemisia Annua L. on Production of Mediators of Angiogenesis.” Pharmacological Reports: PR 65, no. 2 (2013): 410–20. https://www.ncbi.nlm.nih.gov/pubmed/23744425

^[22] Suberu, John O., Alexander P. Gorka, Lauren Jacobs, Paul D. Roepe, Neil Sullivan, Guy C. Barker, and Alexei A. Lapkin. “Anti-Plasmodial Polyvalent Interactions in Artemisia Annua L. Aqueous Extract–Possible Synergistic and Resistance Mechanisms.” PloS One 8, no. 11 (2013): e80790. doi:10.1371/journal.pone.0080790. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828274/

^[23] Takeda, Hiroshi, Minoru Tsuji, Teruhiko Matsumiya, and Masayoshi Kubo. “Identification of Rosmarinic Acid as a Novel Antidepressive Substance in the Leaves of Perilla Frutescens Britton Var. Acuta Kudo (Perillae Herba).” Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology 22, no. 1 (February 2002): 15–22. https://www.ncbi.nlm.nih.gov/pubmed/11917505

^[24] Pereira, Patrícia, Denise Tysca, Paulo Oliveira, Lucimar Filot da Silva Brum, Jaqueline Nascimento Picada, and Patrícia Ardenghi. “Neurobehavioral and Genotoxic Aspects of Rosmarinic Acid.” Pharmacological Research 52, no. 3 (September 2005): 199–203. doi:10.1016/j.phrs.2005.03.003. https://www.ncbi.nlm.nih.gov/pubmed/16026713

^[25] Aldrich, Esther, and Randall Bornemann. Fang Xiang Liao Fa: Essential Oil Analogues of TCM Herbal Formulas. CreateSpace Independent Publishing Platform, 2013. https://books.google.com/books/about/Fang_Xiang_Liao_Fa.html. P. 49.

^[26] Tan, Loh Teng Hern, Learn Han Lee, Wai Fong Yin, Chim Kei Chan, Habsah Abdul Kadir, Kok Gan Chan, and Bey Hing Goh. “Traditional Uses, Phytochemistry, and Bioactivities of Cananga Odorata (Ylang-Ylang).” Evidence-Based Complementary and Alternative Medicine : eCAM 2015 (2015). doi:10.1155/2015/896314. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534619/

^[27] Aldrich, Esther, and Randall Bornemann. Fang Xiang Liao Fa: Essential Oil Analogues of TCM Herbal Formulas. CreateSpace Independent Publishing Platform, 2013. https://books.google.com/books/about/Fang_Xiang_Liao_Fa.html. P. 44.

^[28] Avoseh, Opeyemi, Opeoluwa Oyedeji, Pamela Rungqu, Benedicta Nkeh-Chungag, and Adebola Oyedeji. “Cymbopogon Species; Ethnopharmacology, Phytochemistry and the Pharmacological Importance.” Molecules 20, no. 5 (April 23, 2015): 7438–53. doi:10.3390/molecules20057438. https://www.mdpi.com/1420-3049/20/5/7438/htm

^[29] Akono Ntonga, Patrick, Nicolas Baldovini, Elisabeth Mouray, Lengo Mambu, Philippe Belong, and Philippe Grellier. “Activity of Ocimum Basilicum, Ocimum Canum, and Cymbopogon Citratus Essential Oils against Plasmodium Falciparum and Mature-Stage Larvae of Anopheles Funestus S.s.” Parasite (Paris, France) 21 (2014): 33. doi:10.1051/parasite/2014033. https://www.ncbi.nlm.nih.gov/pubmed/24995776

^[30] Costa, Celso A. Rodrigues de Almeida, Daniele Oliveira Kohn, Valéria Martins de Lima, André Costa Gargano, Jorge Camilo Flório, and Mirtes Costa. “The GABAergic System Contributes to the Anxiolytic-like Effect of Essential Oil from Cymbopogon Citratus (lemongrass).” Journal of Ethnopharmacology 137, no. 1 (September 1, 2011): 828–36. doi:10.1016/j.jep.2011.07.003. https://www.ncbi.nlm.nih.gov/pubmed/21767622

^[31] Blanco, M. M., C. a. R. A. Costa, A. O. Freire, J. G. Santos, and M. Costa. “Neurobehavioral Effect of Essential Oil of Cymbopogon Citratus in Mice.” Phytomedicine: International Journal of Phytotherapy and Phytopharmacology 16, no. 2–3 (March 2009): 265–70. doi:10.1016/j.phymed.2007.04.007. https://www.ncbi.nlm.nih.gov/pubmed/17561386

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